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[DOI] [PMC free article] [PubMed] [Google Scholar] 52.Yang X, Lu X, Lombes M, Rha GB, Chi YI, Guerin TM, et al
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Each COA reports results from third-party laboratory analysis, including: Ultra-high-performance liquid chromatography with mass spectrometry (UHPLC-MS) for purity, typically confirmed at 99% or higher Mass identification for molecular confirmation and content quantitation Endotoxin quantitation by Limulus amebocyte lysate (LAL) assay where applicable Visual and physical characterization of the finished material How to verify a COA independently Every certificate can be checked against the issuing laboratory’s own records, not just the copy hosted here
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