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Zero human clinical trials — a ClinicalTrials.gov search returns no registered study of 5-Amino-1MQ, and the two studies the registry returns for NNMT generally are a terminated hydroxychloroquine trial and an endometrial gene-expression study, neither of which tests an NNMT inhibitor
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High-cost drugs — particularly biologics, chemotherapy agents, and specialty infusions — frequently require prior authorization before the payer will approve reimbursement
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