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GROWTH HORMONE, INSULIN-LIKE GROWTH FACTOR-1 AND THE AGING BRAIN - PMC
Although this study focused on phospholipid synthesis involving ACSL3, esterification of ACSL3 was shown to be a critical step for β-oxidation and lipid droplet formation, which may contribute to ferroptosis vulnerability (Fig
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The proportional increase in upregulated genes under severe stress suggests intensified transcriptional activation of defense−related processes, although overall suppression of growth−related pathways became more pronounced
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