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Based on these results, a phase Ib trial of IOA-289 in combination with standard-of-care chemotherapy is currently ongoing in patients with metastatic pancreatic cancer (clinical trial ID: NCT05586516)
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Additionally, BPC 157 may participate in the brain–gut and gut–brain axis function [9], exerting particular effects when given peripherally [9] (i.e., release of the serotonin in the specific brain areas (i.e., nigrostriatum) [31], opposes the schizophrenia-like positive symptoms models [32], counteracts various encephalopathies [30,33,34,35,36,37,38,39,40,41])
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