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Thereafter, the cells were incubated with primary mouse monoclonal antibody to H2AX (Ser-139) diluted 1 : 1000 (Upstate Biotechnology) or primary antibody anti-cisplatin (CP9/19) (Abcam, Cambridge, MA, USA) that was diluted 1 : 5000 for 16 h at 4 °C

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The lack of standardized dosing protocols, administration techniques, and extended monitoring further hinders clinical translation

GSSG is reduced to GSH