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Here, we describe the case of a 29-year-old woman presenting with skin hyperpigmentation as her only initial symptom after N 2 O abuse for approximately 2 years
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Results obtained with an anti-TfR antibody strongly suggest that iron transported into cells via TfR is responsible for H 2 O 2 -induced DCFH oxidation and that intracellular oxidative stress, caused by GSH depletion, triggers iron signaling and apoptosis [32]
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