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However, consumption of liposomal glutathione (50 mg/kg/day) by atherosclerotic apolipoprotein E-deficient (E 0 ) mice (which develop atherosclerotic lesions with many features common with human lesions) for 2 months significantly reduced serum and macrophage oxidative stress, macrophage cholesterol mass, and as a result of these effects, significantly attenuated atherosclerosis development when compared to mice that consumed similar concentration of control liposomes [66]
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