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4.3 MSA and lipid changes MSA is a rare neurodegenerative synucleinopathy and, in contrast to PD and DLB, associated with the formation of αSyn aggregates in oligodendrocytes referred to as glial cytoplasmic inclusions (GCIs) (Spillantini et al., 1998
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255 For example, the integrin-mediated signaling pathways regulate the expression of genes involved in collagen synthesis and degradation, influencing the mechanical properties of the ACL
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